Bulk flow - factors that influence bulk flow
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• Bulk flow helps regulate the relative volumes of blood and interstitial fluid.
• Flow from blood to interstitium is called filtration.
• Flow from interstitium to blood is called reabsorption.
• Four factors determine the net direction of capillary exchange.
• These factors include:
• Blood hydrostatic pressure (BHP), which pushes fluid out of the capillary and promotes filtration.
• Blood colloid osmotic pressure (BCOP), which acts as if it "pulls" fluid into the capillary and promotes reabsorption.
• Interstitial fluid osmotic pressure (IFOP), which is the slight pull of fluids towards the interstitium promoting filtration.
• Interstitial fluid hydrostatic pressure (IFHP), which is near zero under normal pressure