Chinese scientists establish new method for designing proteins from scratch / 中国科学家建立蛋白质从头设计新方法
Recently, a research team from the University of Science and Technology of China adopted a data-driven strategy to establish a new route for protein de novo design. This method breaks through the limitation of only splicing natural fragments to generate new backbone structures, and can even design novel structures that are different from known natural proteins, laying an important foundation for the design of functional proteins such as industrial enzymes and biological materials.
Huang, B., Xu, Y., Hu, X. et al. A backbone-centred energy function of neural networks for protein design. Nature (2022). https://doi.org/10.1038/s41586-021-04...