Ep 026 - Why do some spirits burn
Hello All,
Time for a new video, this one took a long time to research. But below are all the links I referenced in the video, as well as some other links/studies I used as references, in no specific order.
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Taste Receptor:
https://en.wikipedia.org/wiki/Taste_r...
TRPA1 Receptor:
https://en.wikipedia.org/wiki/TRPA1
TRPV Receptor:
https://en.wikipedia.org/wiki/TRPV1
Deletion of vanilloid receptor (TRPV1) in mice alters behavioral effects of ethanol:
https://www.ncbi.nlm.nih.gov/pmc/arti...
Involvement of TRPV1 Channels in Energy Homeostasis:
https://www.frontiersin.org/articles/...
Oral somatosensory awareness:
https://www.sciencedirect.com/science...
Does sugar make your alcoholic drink less dangerous?:
https://www.sciencedaily.com/releases...
Activation of planarian TRPA1 by reactive oxygen species reveals a conserved mechanism for nociception:
doi:10.1038/s41593-017-0005-0
Infrared Snake Eyes: TRPA1 and the Thermal Sensitivity of the Snake Pit Organ:
https://pubmed.ncbi.nlm.nih.gov/20571...
Mechanisms involved in potentiation of transient receptor potential vanilloid 1 responses by ethanol:
https://pubmed.ncbi.nlm.nih.gov/17826...
MINOR CONSTITUENTS OF WHISKY FUSEL OILS:
https://www.researchgate.net/publicat...
New natural agonists of the transient receptor potential Ankyrin 1 (TRPA1) channel:
https://pubmed.ncbi.nlm.nih.gov/32641...
Noxious Cold Ion Channel TRPA1 Is Activated by Pungent Compounds and Bradykinin:
https://pubmed.ncbi.nlm.nih.gov/15046...
Divalent cations potentiate TRPV1 channel by lowering the heat activation threshold:
https://pubmed.ncbi.nlm.nih.gov/24344...
Ethanol inhibits cold-menthol receptor TRPM8 by modulating its interaction with membrane phosphatidylinositol 4,5-bisphosphate:
https://pubmed.ncbi.nlm.nih.gov/17074...
Chemical Activation of Sensory TRP Channels
https://www.researchgate.net/publicat...
Primary alcohols activate human TRPA1 channel in a carbon
chain length-dependent manner:
https://pubmed.ncbi.nlm.nih.gov/22222....
Hot and Cold TRP Ion Channels:
https://science.sciencemag.org/conten...
Transient receptor potential A1 mediates acetaldehyde-evoked pain sensation:
https://pubmed.ncbi.nlm.nih.gov/17970...
Transient Receptor Potential Channels as Targets for Phytochemicals:
https://pubmed.ncbi.nlm.nih.gov/24926...
TRP channels as cellular sensors:
https://www.nature.com/articles/natur...
TRPV1 and TRPA1 Function and Modulation Are Target Tissue Dependent:
https://pubmed.ncbi.nlm.nih.gov/21775...
Distilling.com 3 part series on 80 years of Rapid Maturation Studies:
If you are having trouble reading all 3, due to the article limit they placed, just disable cookies for "distilling.com", and it should work.
Part 1: https://distilling.com/distillermagaz...
Part 2: https://distilling.com/distillermagaz...
Part 3: https://distilling.com/distillermagaz...
Congener Development in Bourbon Whisky Matured at Various Proofs for Twelve Years:
https://academic.oup.com/jaoac/articl...
Acute Alcohol Action and Desensitization of Ligand-Gated Ion Channels:
https://pubmed.ncbi.nlm.nih.gov/19270...
Deletion of vanilloid receptor (TRPV1) in mice alters behavioral effects of ethanol:
https://pubmed.ncbi.nlm.nih.gov/19705...
Effect of impurity compounds on ethanol hydration:
https://www.sciencedirect.com/science....
Effects of Salts, Acids, and Phenols on the Hydrogen-Bonding Structure of Water-Ethanol Mixtures:
https://pubs.acs.org/doi/abs/10.1021/...
Hydrogen Bonding of Water–Ethanol in Alcoholic Beverages:
https://pubmed.ncbi.nlm.nih.gov/17116...
Identification of compounds that contribute to trigeminal burn in aqueous ethanol solutions:
https://pubmed.ncbi.nlm.nih.gov/27283...
Interaction between water and ethanol via hydrogen bonding in alcoholic beverages:
https://www.researchgate.net/publicat...
Unfortunately, there were too many, and I couldn't include them all.