ACR - Loot 6 speed run with chests
Assassin's Creed Rebellion
Using semi-auto.
Perfect health is assumed because anytime you lose health you're slowing down.
No Elite Training needed.
Required: Initiative buff
Domingo - Initiative buff. He's used for other missions so I don't have to switch him out.
Tereysa - Fast attack animation. Need her for other missions and I don't have to switch her out.
Gaspar - Healing Tereysa if I need to, usually don't.
It's very random who Auto choose to take into the trap room. From there you should play it safe and just manually go up and then left for first chest, there's a variety of choices for Auto to make and I haven't seen a consistent pattern for which paths it chooses. Switch back to Tereysa if you want to, both Dom and Gaspar have slower attacks, but not by much. I like to stay consistent regardless.
After the first chest there's a 50/50 chance for Auto to take the lower path to second chest. You can go there manually but that takes more time. If Auto choose upper path that would definitely take even more time, but it's only by a few extra second over the manual move. Since half of the runs it's taking the lower path anyway, the time split between manually moving there and Auto taking the upper path is close enough that you should chance it.