Immunotherapy for Alzheimer’s disease shows promise
Scientists at Washington University School of Medicine in St. Louis have found a different and promising way to remove noxious plaques in the brains of people with Alzheimer's disease: by mobilizing immune cells to consume the plaques.
The researchers showed that activating immune cells called microglia with an antibody reduces amyloid plaques in the brain and mitigates behavioral abnormalities in mice with Alzheimer’s-like disease.
The approach could also help people suffering from other diseases. Toxic clumps of brain proteins are features of many neurodegenerative conditions, including Parkinson’s disease, amyotrophic lateral sclerosis (ALS) and Huntington’s disease.
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