Dr. S. Allen Luis, an Associate Professor of Medicine at the Mayo Clinic in Rochester, MN, shares results of his study appearing in the July 2021 issue of Mayo Clinic Proceedings, where the study confirmed prior findings that cardiac magnetic resonance (CMR) imaging carries a high diagnostic yield in patients with a “working diagnosis” of myocardial infarction with non-obstructive coronary arteries (MINOCA). More importantly, it demonstrates that CMR diagnoses predicted long-term prognosis. Interestingly and unexpectedly, to demonstrated that “true” MINOCA patients (i.e. those with normal cardiac magnetic resonance imaging) had an increased rate of major adverse cardiac events, which may in turn may be related to the lower use of guideline-recommended myocardial infarction therapy in these patients when compared with those with cardiac magnetic resonance-confirmed myocardial infarction. Available at: https://mayocl.in/2SYKp8Z