In Chapter 10 of A Plague Tale: Innocence, "The Way of Roses," Amicia and Rodric infiltrate the University to retrieve the Sanguinis Itinera book. After traversing a library and dealing with guards, they find the book, leading to a tense confrontation with Vitalis before escaping through a burning building.
The pair navigates a maze-like basement filled with forbidden books, utilizing a mechanism to reach the Sanguinis Itinera. Grand Inquisitor Vitalis arrives, confirming he has been monitoring the de Rune family and wants the Prima Macula within Hugo's blood. As the building is set ablaze, Amicia and Rodric make a narrow escape, with Rodric assisting in forcing open a path.
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