This animation was simulated in a fluid simulation program that I am writing. The program outputs a triangle mesh for each simulated frame which is then imported into Blender and rendered using Cycles.
Simulation visualization was rendered in Blender.
Simulation Details:
Frames 553
Simulation time 39.3 hours
Render time 50.7 hours (100 samples)
Total time 90.0 hours
Simulation resolution 422 x 244 x 128
Mesh Resolution 844 x 488 x 256
Peak # of particles 15.0 Million
Peak RAM usage 2.5 GB
Bake file size 27.4 GB
Computer specs: ultrabook style laptop with Intel Core i5-4200U @ 1.60GHz processor, integrated Intel HD4400 graphics chip, and 8GB RAM.
Source Code: https://github.com/rlguy/GridFluidSim3D